● Provides up to 20 hours of moisture ● Contains 25% more Hyaluronan* ● Contains an added electrolyte and antioxidant to preserve balance of the ocular surface and to protect hyaluronan against free radicals ● Triple Disinfectant System kills 99.9% of all germs tested** ● *vs original Biotrue formula ● ** Standardized testing (ISO 14729) against S. aureus, P. aeruginosa, S. marcescens, C. albicans, F. solani

Directions: To condition, clean, remove protein and disinfect lenses daily, complete these simple steps. STEP 1: Place at least 3 drops of Biotrue ADVANCED multi-purpose solution on each side of lens surface and gently rub for 20 seconds. STEP 2: Thoroughly rinse each side of the lens for 5 seconds with Biotrue ADVANCED multi-purpose solution. STEP 3: Place cleaned contact lenses in the lens case and fill with fresh Biotrue ADVANCED multi-purpose solution. Soak at least 4 hours.

Warnings
IMPROPER USE OF CONTACT LENSES AND LENS CARE PRODUCTS COULD RESULT IN CORNEAL INFECTION AND/OR ULCER AND LEAD TO LOSS OF VISION. It is essential that you follow your eye care professional’s directions and all labelling instructions for proper use of lenses and lens care products, including the lens case. Eye problems, including corneal ulcers, can develop rapidly and lead to loss of vision. Daily wear lenses are not indicated for overnight wear and should not be worn while sleeping. Clinical studies have shown the risk of serious adverse reactions is increased when these lenses are worn overnight. Extended wear lenses should be regularly removed for cleaning and disinfection or for disposal and replacement on the schedule prescribed by your eye care professional. Clinical studies have shown that there is an increased incidence of serious adverse reactions in extended wear contact lens users as compared to daily wear contact lens users. Studies have also shown that the risk of serious adverse reactions increases the longer extended wear lenses are worn before removal for cleaning and disinfection or for disposal and replacement. Studies have also shown that smokers have a higher incidence of adverse reactions. If you experience eye discomfort, excessive tearing, vision changes, redness of the eye, immediately remove your lenses and promptly contact your eye care professional. It is recommended that you see your eye care professional regularly, to assure the continued health of your eyes. You should follow the complete recommended lens rubbing and rinsing times in the product labeling to adequately disinfect your lenses and reduce the risk of contact lens contamination. Reduced rubbing or rinsing time may not adequately clean your lenses. Failure to discard solution from lens case after each use or use of water to care for your lenses may lead to contamination resulting in eye injury and potential loss of vision. See accompanying instructions for additional important safety information. Important Safety Information: • Visit your eye care professional regularly. • To avoid contamination, do not touch tip of container to any surface. Replace cap after using. • Do not use with heat (thermal) disinfection. • Do not instill Biotrue® ADVANCED directly in the eye. Precautions: • Store solution at room temperature. • Use before the expiration date marked on the carton and bottle. • Discard any remaining solution 90 days after opening.

Hyaluronan (HA), diglycine, erythritol, poloxamine, poloxamer 181, sodium citrate, boric acid, sodium borate, edetate disodium and potassium chloride, and preserved with a triple disinfectant system (polyaminopropyl biguanide 0.00005%, polyquaternium 0.00015% and alexidine 0.00025%.)