Medication reactions and psoriasis

Certain medications may be associated with worsening symptoms of psoriasis:

Antimalarial medications: Chloroquine and hydroxychloroquine are medications used to prevent malaria that may worsen the symptoms of psoriasis.

Beta-blockers and some heart medications: These medications are used to treat high blood pressure and other heart conditions. Doctors are uncertain if all heart medications, including beta-blockers, can worsen psoriasis flare-ups, but they believe that some (e.g., propranolol, metoprolol, quinidine) have the potential to do so.

Some nonsteroidal anti-inflammatory medications (NSAIDs):

  • ibuprofen
  • acetylsalicylic acid (ASA)
  • indomethacin

Lithium: This medication is used to help treat people with bipolar disorder (also known as manic-depressive disorder) and some other psychiatric disorders. Some people with psoriasis who take this medication experience a worsening of symptoms.

Let your doctor know that you have psoriasis before any medications are prescribed for you. If you have other conditions that may require prescription or over-the-counter medications, ask your doctor, dermatologist, or pharmacist which combination of medications (i.e., for psoriasis and other unrelated conditions) would be most appropriate for you.

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