The FreeStyle Libre 2 System (FreeStyle Libre 2 Reader or FreeStyle Libre 2 app used with FreeStyle libre 2 Sensor) is designed to replace blood glucose testing in the self-management of diabetes, including dosing insulin, in people aged 4 years and older with diabetes mellitus. The System measures glucose levels from the interstial fluid - a thin layer of fluid that surrounds the cells of the tissues in your skin. Glucose is found in the interstial fluid because it moves there from blood vessels. The FreeStyle Libre 2 system is...§ Informative - Optional, real-time glucose alarms let you know the minute your glucose is too low or too high Convenient - Sensor automatically updates glucose readings every minute and sends them directly to your smartphone.* Discreet - Painless2 glucose readings with a 1-second scan, even through clothing¶ Easy - The FreeStyle Libre 2 sensor: o Is designed to stay on the body for up to 14 days1 o Is water-resistant and designed to be worn while bathing, showering, swimming‡ or exercising Accurate - No routine confirmatory finger pricks† required for treatment decisions, even when glucose is low, falling or rapidly changing Reduces A1C - Clinically proven to: o Lower A1C without increasing hypoglycemia3 o Improve time in range4 Covered - Covered publicly in many provinces and by most private health insurance plans

Applying your sensor: 1. Wash using only non-moisturing, fragrance-free soaps to the area that you will apply your sensor. 2. Clean using the alcohol wipe provided in the sensor kit to remove any oily residue on the skin. 3. Dry and allow your skin to fully dry before applying the sensor. Tips: 1. Shave any excess arm hair as it can get caught between the sensor adhesive and skin 2. After a shower or swim, take extra care when towelling off to avoid catching or pulling the sensor 3. Try to give your sensor room by wearing loose-fitting clothing and lightweight material 4. Be sure to select a site on the back of your upper arm that will minimize the risk of it coming off, and consider using an over-bandage and/or any of the items on the previous page 5. Avoid playing with or pulling the sensor while wearing it Making your sensor stay put: Add extra stickiness with these products to help ensure your sensor stays in place. 1. Torbot Skin Tac - https://torbot.com/ 2. Skin-Prep Protective Wipes - https://www.smith-nephew.com/ 3. Mastisol Liquid Adhesive - https://eloquesthealthcare.com/ 4. Calilon No-Sting Barrier Film - https://www.3mcanada.ca/3M/en_CA/company-ca/ 5. Tagaderm I.V. - https://www.3mcanada.ca/3M/en_CA/company-ca/ 6. Over-Bandage - A medical-grade adhesive; bandage or tape. If using, it must be applied at the time of sensor application. It is important that you only remove it when your sensor wear is over as the sensor may come loose when peeling it off. Be sure to leave the opening/hole in the centre of the sensor uncovered so it can breathe.

Warnings
Contradindication: Remove the Sensor that you are wearing if you have a medical appointment that includes strong magnetic or electromagnetic radiation, e.g. an X-ray, MRI (Magnetic Resonance Imaging) or CT (Computed Tomography) scan. Apply a new Sensor after the appointment. Warnings: - Do not ignore symptoms that may be due to low or high blood glucose. If youhave symptoms that do not match the Sensor glucose reading or suspect that your reading may be inaccurate, check the reading by conducting a fingerstick test using a blood glucose meter. If you have symptoms that do not match your glucose readings, consult your healthcare professional. - If you are using FreeStyle Libre 2 app, you must have access to a blood glucose monitoring system as the App does not provide one. - Choking hazard: The System contains small parts that may be dangerous if swallowed. Cautions and Important Information: What to know about Glucose Alarms - For you to receive alarms, they must be on, and your phone should be within 6 metres (20 ft) of you at all times. The transmission range is 6 metres (20 ft) unobstructed. If you are out of range, you may not receive glucose alarms. - Do not force close the App. - Check to make sure that you have the correct settings and permissions enabled on your phone to receive alarms. - Enable Bluetooth and Notifications for the App. Be sure not to turn on any features or modify phone settings that may interrupt the presentation of notifications. - Turn on Lock Screen notifications, Banner Notifications, Notification sounds and general phone sounds or vibration. - Turn off Do Not Disturb mode or select to turn on Override Do Not Disturb in your alarm settings. Do this if you want the alarm to always play a sound and appear on the lock screen even if your phone is muted or Do Not Disturb is on. Note: You must accept the App’s permission request for Critical Alerts to use this feature. You can also enable the Critical Alerts setting directly from the App’s notification settings. - Remember that alarm settings will follow your phone’s sound and vibration settings, so these should be at a level that you can hear to prevent missed alarms. - You should disconnect headphones when you are not using them as you may not receive audio with alarms. - If you are using peripheral devices connected to your phone, such as wireless headphones or a smartwatch, you may receive alarms on only one device or peripheral, not all. - Keep your phone well charged and turned on. Who should not use the System - The System has not been evaluated for use with other implanted medical devices, such as pacemakers. - The System has not been evaluated for use in pregnant women, persons on dialysis or people less than 4 years of age. - Do not use the System if you are critically ill. The System has not been evaluated for use by critically ill patients and it is not known how different conditions or medications common to this population may affect performance of the System. What to know about wearing the Sensor - Some individuals may be sensitive to the adhesive that keeps the Sensor attached to the skin. If you notice significant skin irritation around or under your Sensor, remove the Sensor and stop using the System. Do not try to treat any skin irritation with lotions/creams/ointments/sprays/barrier patches in order to continue wearing the Sensor. Contact your healthcare professional before continuing to use the System. - Intense exercise may cause your Sensor to loosen due to sweat or movement of the Sensor. If your Sensor comes loose, you may get no readings or unreliable readings, which may not match how you feel. Follow the instructions to select an appropriate application site. - Glucose Going Low and Glucose Going High messages may mean that your actual blood glucose is already <3.9 mmol/L or >13.3 mmol/L. Consider this before making an activity or treatment decision. - If you are going to participate in activities that could result in harm to yourself or others in the event of a severe hypoglycaemic episode (e.g. driving a motor vehicle without following the Canadian Diabetes Association Recommendations for Private and Commercial Drivers), do not rely on Glucose Messages (High Glucose, Low Glucose, Glucose Going High and Glucose Going Low) alone. Talk to your healthcare professional about checking your glucose before and while driving. - When using the System to replace blood glucose testing for making diabetes treatment decisions, including insulin dosing, you should have a good understanding of how to self-manage your diabetes, as determined by your healthcare professional. How to store the Sensor Kit - Store the Sensor Kit between 4°C and 25°C. While you don’t need to keep your Sensor Kit in a refrigerator, you can as long as the refrigerator is between 4°C and 25°C. When not to use the System - Do NOT use if the Sensor Pack or the Sensor Applicator seem to be damaged or already opened. - Do NOT use if past expiry date. What to know before you apply the Sensor - Clean the application site and ensure that it is dry prior to Sensor insertion. This helps the Sensor stay attached to your body. When is Sensor Glucose different from Blood Glucose - Glucose levels in the interstitial fluid can be different from blood glucose levels and may mean that Sensor glucose readings are different from blood glucose. You may notice this difference during times when your blood glucose is changing quickly, for example after eating, taking insulin or exercising. When to remove the Sensor - If the Sensor is becoming loose or if the Sensor tip is coming out of your skin, you may get no readings or unreliable readings, which may not match how you feel. Check to make sure your Sensor has not come loose. If it has come loose, remove it and apply a new one. - On rare occasions, you may get inaccurate Sensor glucose readings. If you believe your glucose readings are not correct or do not match how you feel, perform a blood glucose test on your finger to confirm your glucose. If the problem continues, remove your Sensor and apply a new one. What to know about FreeStyle Libre 2 app - FreeStyle Libre 2 app installed on a smartphone is intended for use by a single person. It must not be used by more than one person due to the risk of misinterpreting glucose information. Interfering Substances: - Taking more than 500 mg of ascorbic acid per day may affect the Sensor readings which could cause you to miss a low glucose event. Ascorbic acid can be found in supplements including multivitamins. Some supplements, including cold remedies, may contain high doses of 1000 mg of ascorbic acid. Do not use the Sensor while taking supplements that contain high doses of 1000 mg of ascorbic acid.